Reprints of all papers are available on request
On the low-frequency dispersion observed in dielectrophoresis spectra. MP Hughes, KSP Clarke, R Hoque, OV Griffiths, EJ Kruchek, F Bertagna, K Jeevaratnam, R Lewis, FH Labeed. Electrophoresis 2024 (in press)
Mechanisms and physiological function of daily haemoglobin oxidation rhythms in red blood cells. AD Beale, P Crosby, UK Valekunja, RS Edgar, JE Chesham, ES Maywood, FH Labeed, AB Reddy, KP Wright Jr, KS Lilley, D Bechtold, MH Hastings, JS O’Neill. EMBO Journal 2023 42 e114164.
Point-of-care Analysis for Non-invasive Diagnosis of Oral cancer (PANDORA): a technology-development proof of concept diagnostic accuracy study of dielectrophoresis in patients with oral squamous cell carcinoma and dysplasia. MP Hughes, FH Labeed, KF Hoettges, S Porter, V Mercadante, N Kalavrezos, C Liew, JA McCaul, R Kulkarni, J Cymerman, C Kerawala, J Barber, MP Lewis, S Fedele. Journal of Oral Pathology and Medicine 2023 52 305-314.
Circadian rhyhmicity in murine erythrocytes: Effect of malarial infection and anaemia. FH Labeed, AD Beale, P Schneider, SJ Kitcatt, EJ Kruchek, R Abdallat, SE Reece. Frontiers in Bioengineering and Biotechnology 202210 994487.
Detecting Circadian Rhythms in Human Red Blood Cells by Dielectrophoresis. AD Beale, FH Labeed, SJ Kitcatt, JS O’Neill. Methods in Molecular Biology 2022 2482 255-264.
The platelet electrome: evidence for a role in regulation of function and surface interaction. MP Hughes, EJ Kruchek, J Gibbins, OV Griffiths, B Abdal, FH Labeed. Bioelectricity 2022 4 153-159.
Cytoplasmic anion/cation imbalances applied across the membrane capacitance may form a significant component of the resting membrane potential of red blood cells. MP Hughes, CH Fry, FH Labeed. Scientific Reports 2022 12 15005
In Vitro characterization of murine pre-adipose nucleated cells reveals electrophysiological cycles associated with biological clocks C Martin, JD Johnston, EA Henslee, DR can der Veen, FH Labeed Electrophoresis 2022 43 1337-1346
Electrophysiological Changes in Osteoarthritis R Abdallat, EJ Kruchek, C Matta, R Lewis, FH Labeed Micromachines 2021 12 949
Vm-related extracellular potentials observed in red blood cells. MP Hughes, EJ Kruchek, AD Beale, SJ Kitcatt, S Qureshi, ZP Trott, O Charbonnel, PA Agbaje, EA Henslee, RA Dorey, R Lewis, FH Labeed. Scientific Reports 2021 11 19446
Transcriptome-based screening of ion channels and transporters in a migratory chondroprogenitor cell line isolated from late-stage osteoarthritic cartilage. C Matta, R Lewis, C Fellows, G Diszhazi, J Almassy, N Miosge, J Dixon, MC Uribe, S May, S Poliska, R Barrett-Jolley, E Henslee, FH Labeed, MP Hughes, A Mobasheri. Journal of Cellular Physiology 2021 236 7421-7439
DEP-Dots for 3D cell culture: low-cost, high-repeatability, effective 3D cell culture in multiple gel systems EA Henslee, CM Dunlop, CM de Mel, EA Carter, RG Abdallat, P Camelliti, FH Labeed, Scientific Reports 2020 10 14603
Casein Kinase 1 underlies temperature compensation of circadian rhythms in human red blood cells AD Beale, E Kruchek, SJ Kitcatt, EA Henslee, JSW Parry, G Braun, R Jabr, M von Schantz, JS O’Neill, FH Labeed. Journal of Biological Rhythms 2019 34 144-153
Ten–Second Electrophysiology: Evaluation of the 3DEP Platform for high-speed, high-accuracy cell analysis KF Hoettges, EA Henslee, RM Torcal Serrano, RI Jabr, RG Abdallat, AD Beale, A Waheed, P Camelliti, CH Fry, DR van der Veen, FH Labeed, MP Hughes, Scientific Reports 2019 9 19153
Dielectrophoretic analysis of treated cancer cells for rapid assessment of treatment efficacy. S Mahabadi, FH Labeed, MP Hughes, Electrophoresis 2018 39 1104-1110
Rhythmic K+ transport regulates the circadian clock in human red blood cells EA Henslee, P Crosby, SJ Kitcatt, JSW Parry, A Bernardini, RG Abdallat, G Braun, HO Fatoyinbo, EJ Harrison, KF Hoettges, AB Reddy, Rachel S. Edgar, RI Jabr, M von Schantz, JS O’Neill, FH Labeed, Nature Communications 2017 8 1978.
High-Throughput, Low-Loss, Low-Cost and Label-Free Cell Separation using Electrophysiology Activated Cell Enrichment SA Faraghat, KF Hoettges, MK Steinbach, D van der Veen, WJ Brackenbury, EA Henslee, FH Labeed and MP Hughes, Proceedings of the National Academy of Sciences of the USA 2017 114 4591-4596
Electrospun oriented gelatin-hydroxyapatite fibre scaffolds for bone tissue engineering A Salifu, C Lekakou, FH Labeed Journal of Biomedical Materials Research: Part A 2017 105 779-789
Smooth muscle tissue engineering in crosslinked electrospun gelatin scaffolds Y Elsayed, C Lekakou, FH Labeed, P Tomlins Journal of Biomedical Materials Research part A 2016 104 313–321
Accurate quantification of apoptosis progression and toxicity using a dielectrophoretic approach EA Henslee, RM Torcal Serrano, FH Labeed, RI Jabr, CH Fry, MP Hughes, KF Hoettges Analyst 2016 141 6408-6415
Fabrication and characterisation of biomimetic, electrospun gelatin fibre scaffolds for tunica media-equivalent, tissue engineered vascular grafts Y Elsayed, C Lekakou, F Labeed, and P Tomlins Materials Science & Engineering C-Materials for Biological Applications 2016 61 473-483
Characterisation of human skeletal stem and bone cell populations using dielectrophoresis A Ismail, MP Hughes, HJ Mulhall, ROC Oreffo, FH Labeed Journal of Tissue Engineering and Regenerative Medicine 2015 9 162-168
The effects of cell detachment methods on the dielectric properties of adherent and suspension cells S Mahabadi, FH Labeed, MP Hughes Electrophoresis 2015 36 1493–1498
A dielectrophoretic method of discrimination between normal oral epithelium, and oral and oropharyngeal cancer in a clinical setting KA Graham, HJ Mulhall, FH Labeed, MP Lewis, KF Hoettges, N. Kalavrezos, J McCaul, C Liew, S Porter, S Fedele, MP Hughes Analyst 2015 140 5198-5204
Apoptosis Progression Studied using Parallel Dielectrophoresis Electrophysiological Analysis and Flow Cytometry HJ Mulhall, A Cardnell, KF Hoettges, FH Labeed and MP Hughes Integrative Biology 2015 7 1396-1401
Human oral cancer cells with increasing tumorigenic abilities exhibit higher effective membrane capacitance X Liang, KA Graham, AC Johannessen, DE Costea, FH Labeed Integrative Biology 2014 6 545-554
Process development for cell aggregate arrays encapsulated in a synthetic hydrogel using negative dielectrophoresis RG Abdallat, AS Ahmad Tajuddin, DH Gould, MP Hughes, HO Fatoyinbo, FH Labeed Electrophoresis 2013 34 1059-1067
Epithelial cancer cells exhibit different electrical properties when cultured in 2D and 3D environments HJ Mulhall, MP Hughes, B Kazmi, MP Lewis, FH Labeed Biochimica et Biophysica Acta 2013 1830 5136-5141
Efficient dielectrophoretic cell enrichment using a DEP-well based system MA Abdul Razak, KF Hoettges, HO Fatoyinbo, FH Labeed, MP Hughes Biomicrofluidics 2013 7 064110 1-10
Cytoplasm Resistivity of Mammalian Atrial Myocardium Determined by Dielectrophoresis and Impedance Methods A Manazza, S Salvage, CH Fry, F Labeed, M Hughes, RI Jabr Biophysical Journal 2012 103 2287-2294
Cell Membrane Analysis using Modulated Dielectrophoresis MMM Elnasharty, AM Ghoneim, GM Turky, M Kamal, FH Labeed, MP Hughes, KF Hoettges Romanian Journal of Biophysics 2012 22 235-246
Gelatine and gelatine/elastin nanocomposites for vascular grafts: processing and characterization D Lamprou, P Zhdan, F Labeed, C Lekakou Journal of biomaterials Applications 2011 26 209-226
Biophysical characteristics reveal neural stem cell differentiation potential FH Labeed, J Lu, HJ Mulhall, SA Marchenko, KF Hoettges, LC Estrada, Laura AP Lee, MP Hughes, LA Flanagan PloS One 2011 6 e25458
Effects of thermal treatments on protein adsorption of Co-Cr-Mo ASTM-F75 alloys L Duncan, FH Labeed, ML Abel, A Kamali, JF Watts Journal of Material Science: Materials in Medicine 2011 22 1455-1464
Cancer, pre-cancer and normal oral cells distinguished by dielectrophoresis HJ Mulhall, FH Labeed, B Kazmi, DE Costea, MP Hughes, MP Lewis Analytical and Bioanalytical Chemistry 2011 401 2455-2463
Real-time cell electrophysiology using a multi-channel dielectrophoretic-dot microelectrode array HO Fatoyinbo, NA Kadri DH Gould, KF Hoettges, FH Labeed Electrophoresis 2011 32 2541-2549
Adhesion of microorganisms to bovine submaxillary mucin coatings: Effect of coating deposition conditions IL Bushnak, FH Labeed, RPL Sear, JL Keddie Biofouling 2010 26 387-397
Action potential recording from dielectrophoretically positioned neurons inside micro-wells of a planar microelectrode array MP Hughes FH Labeed, FT Jaber Journal of Neuroscience Methods 2009 182 225-235
Dielectrophoretic separation of Bacillus subtilis spores from environmental diesel particles HO Fatoyinbo, MP Hughes, SP Martin, P Pashby, FH Labeed Journal of Environmental Monitoring 2007 9 87-90
Early detection of oral cancer-is dielectrophoresis the answer? LM Broche, N Bhadal, MP Lewis, S Porter, MP Hughes, FH Labeed Oral Oncology, 2007 43 199-203
Biophysical characterization of MDR breast cancer cell lines reveals the cytoplasm is critical in determining drug sensitivity HM Coley, FH Labeed, H Thomas, MP Hughes Biochimica et Biophysica Acta 2007 1770 601-608
Dielectrophoretic analysis of changes in cytoplasmic ion levels due to ion channel blocker action reveals underlying differences drug sensitive and multidrug resistant leukaemic cells L Duncan, H Shelmerdine, Y. Hübner, HM Coley, MP Hughes, FH Labeed Physics in Medicine and Biology, 2008 53 N1-N7
Differences in the biophysical properties of membrane and cytoplasm of apoptotic cells revealed using dielectrophoresis FH Labeed, HM Coley, MP Hughes Biochimica et Biophysica Acta 2006 1760 922-929
Dielectrophoresis is a rapid technique for detecting early apoptosis S Chin, MP Hughes, HM Coley, FH Labeed International Journal of Nanomedicine, 2006 1 333-337
Extraction of dielectric properties of multiple populations from dielectrophoretic collection spectrum data LM. Broche, FH Labeed, MP Hughes Physics in Medicine and Biology 2005 50 2267-2274
Assessment of multidrug resistance reversal using dielectrophoresis and flow cytometry FH Labeed, HM Coley, H Thomas, MP Hughes Biophysical Journal 2003 85 2028-2034
for cellular electrophysiology